MiraVista COVID-19 Annoucement

MiraVista is open and continues to provide critical diagnostic testing despite the impact COVID-19 has had on staffing. The health and welfare of our team is of critical importance. To limit the opportunity of exposure to COVID-19 for our entire…
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MiraVista Diagnostics LLC has formed an Institutional Biosafety Committee (IBC)

In compliance with the National Institutes of Health Office of Science Policy (NIH OSP), MiraVista Diagnostics LLC has formed an Institutional Biosafety Committee (IBC) to review, approve and confirm that the company’s research involving recombinant/synthetic DNA complies with NIH guidelines….
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Medical Technologist/Medical Laboratory Scientist: Full Time, Mon.-Fri., Day Shift

MiraVista Diagnostics is hiring full time Medical Technologists (Medical Laboratory Scientists) for the day shift at our clinical lab in Indianapolis. This position is part of the Clinical Services Team and works Monday – Friday 8:00 a.m. – 5:00 p.m….
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Diagnosis of Histoplasma Meningitis by Combined Testing for Antigen and IgG & IgM Antibody in Cerebrospinal Fluid

BACKGROUND: Central nervous system (CNS) histoplasmosis often goes unrecognized, delaying diagnosis and treatment, resulting in neurologic complications or death. It occurs in 5% to 10% of patients with disseminated histoplasmosis, and despite clinical suspicion of CNS involvement, laboratory confirmation can…
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Diagnosis of Progressive Disseminated Histoplasmosis (PDH)

Background. Culture is the gold standard for diagnosis [1] and the sensitivity ranges from about 60 to 80% [2-5] (Table 1). However, growth of Histoplasma is slow, taking up to six weeks and culture rarely provides the initial basis for…
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Diagnosis of Acute Pulmonary Histoplasmosis Can Be Challenging.

Acute pulmonary histoplasmosis is characterized by fever, cough, chest pain, and mediastinal lymphadenopathy with infiltrates. Because presentation resembles other diseases, diagnosis can be challenging. Though antigen detection is highly sensitive in disseminated histoplasmosis (>90%), [1-5], up to 17% of acute…
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Characterization of an Uncinocarpus Reesii-expressed Recombinant Tube Precipitin Antigen of Coccidioides Posadasii for Serodiagnosis

Early and accurate diagnosis of coccidioidomycosis, also known as Valley fever, is critical for appropriate disease treatment and management. Current serodiagnosis is based on the detection of patient serum antibodies that react with tube precipitin (TP) and complement fixation (CF)…
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Peripheral Blood Smear Findings in a Kidney Transplant Recipient with Disseminated Histoplasmosis and Elevated Aspergillus Galactomannan.

We report a case of disseminated histoplasmosis in a renal transplant recipient who presented with a nodular pulmonary lesion and elevated serum and bronchoalveolar lavage (BAL) Aspergillus galatomannan. This almost led to an erroneous diagnosis of invasive aspergillosis since the…
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ID Week: Advances in Diagnosis of Progressive Coccidioidomycosis

Dr. Joseph Wheat presenting Thursday, October 3, 2019 at ID Week Session Date: Thursday, October 3, 2019 Session Time: 12:15 PM – 1:30 PM Stop by poster 236 on October 3rd, 12:15PM – 1:30PM, to speak with Dr. Wheat. Event…
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Heightened Need for Awareness of Coccidioidomycosis

Coccidioidomycosis, also known as Valley Fever, has been drawing the attention of government officials and legislature. Last year, the California budget allocated $8 million for research and outreach to combat the disease, with funding split between the University of California,…
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