From the Desk of Dr. Wheat

Every day, I’m amazed at the fascinating news and innovations that are constantly helping to advance the field of fungal diagnostics and testing. Below are some of the recent stories I’ve found the most interesting. Please take a minute to read along; I hope you’ll be as engaged as I was!

Recent Studies

An Interesting Case

QUESTION: Which triazoles are effective alternatives to itraconazole for treatment of histoplasmosis? ANSWER: Evidence suggests that fluconazole is not adequate. Information about the other triazoles is insufficient to make an evidence-based choice. However, posaconazole appears to be the best alternative….
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Noninvasive Diagnosis of Central Nervous System Blastomycosis

QUESTION: What do you think is the most sensitive test for diagnosis? Culture Pathology Molecular Antigen detection Antibody detection ANSWER: A recently published case report and literature review provides insight into the diagnostic approach, which we have supplemented with literature…
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Nonculture Diagnosis of Central Nervous System Coccidioidomycosis

A previously healthy young man from California presented with a one-month history of headache and intermittent fever. Physical examination was unremarkable. CSF contained 123 leukocytes/µl, 72% mononuclear cells. Protein was 103 mg/dl and glucose 26 mg/dl. No organisms were seen…
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