ASPERGILLUS ANTIBODY IMMUNODIFFUSION
-
Test Code
324
-
CPT Code
86606
-
Clinical Significance
The aspergillus antibody immunodiffusion test is used for the in vitro determination of precipitating antibodies to Aspergillus sp. It is also used as an aid in the diagnosis of Aspergillosis. Aspergillus antigen is represented by one or more precipitin bands and is indicative of infection, colonization or allergy to an Aspergillus sp. Generally speaking, the greater the number of precipitin bands the higher the probability of infection caused by a member of this genus.
-
Methodology
Fungal Immunodiffusion
-
Limitations
The result is not intended to be used as the sole means for clinical diagnosis or patient management decisions.
- False positive results may occur in patients with inflammatory disease.
- False negative results may occur in patients receiving long-term antifungal or corticosteroid therapy.
-
Specimen Collection
Serum/Plasma: Separated from the clot in a leak-proof conatiner.
CSF: Sterile leak-proof container.
-
Minimum Specimen Requirements
Serum/Plasma/CSF: 0.25 mL per antibody
-
Specimen Stability
- Refrigerated: 3 days
- Frozen: indefinite
-
Specimen Rejection
Any specimen types other than serum, plasma, or CSF.
-
Transport Temperature
Refrigerated/Frozen
-
Shipping
Ship on dry ice to arrive Monday‐Friday using a next day delivery service. Frozen ice packs may be substituted if sample is shipped the day of collection.
-
Turnaround Time
2 days from set up date.
-
Reference Range
Antibody not detected.
-
Interpretative Information
- Negative: Antibody not detected
- Positive: Antibody detected
* New positives may require confirmation.
** Turnaround times are provided as ranges, and may vary depending on daily testing volumes and specimen type.
*** Test set-up: Samples received by 10:30 AM are eligible for same-day testing. Same-day testing is not guaranteed and may vary based on daily test volume, sample receipt time, testing schedules, and sample type. Some samples may require pretreatment and/or confirmatory testing, which can extend turnaround time (TAT).